The immunophenotyping of different stages of BK virus allograft nephropathy
نویسندگان
چکیده
منابع مشابه
Immunophenotyping in BK Virus Allograft Nephropathy Distinct from Acute Rejection
Differentiating BK virus nephropathy (BKVN) from acute rejection (AR) is crucial in clinical practice, as both of them have interstitial inflammation in the grafts. The purpose of the study is to describe the inflammatory cellular constituents of BKVN and to determine the clinical utility of immunophenotyping findings in distinguishing BKVN from AR. In addition, the expression of the HLA-DR was...
متن کامل[BK-virus-associated Nephropathy].
The infection by the BK Polyomavirus (BKV) is an emerging problem in kidney transplants that contributes to a chronic loss of kidney grafts, and in which immunosuppression plays a decisive role. Understanding its risk factors and strictly monitoring urine and serological markers of the infection could mitigate the undesirable effects of this disease. In this review, we investigate the clinical ...
متن کاملBK Virus Associated Nephropathy, a Cause of Early Renal Allograft Dysfunction: A Single Centre Study.
BACKGROUND BK virus associated nephropathy (BKVN) is an important cause of early graft dysfunction in renal transplant recipients. The present study was carried out to determine the burden of BKVN in a single renal transplant centre in Australia. METHOD A retrospective analysis of de novo renal transplant recipients from 2010 to 2013 was performed to identify biopsy proven BKVN. Estimated glo...
متن کاملSurveillance Renal Allograft Biopsy on Diagnosis of BK Virus Nephropathy in Chinese Renal Transplant Recipients
Objective: We prospectively investigated 121 renal allograft biopsy specimens performed in our center. Methods: BKVAN was diagnosed by light microscopic examination and a positive immunohistochemistry staining of anti-SV40 large T antibody in a biopsy specimen. Results: Of the 121 patients, nine were diagnosed with BKVAN (7.4%). Nine patients with BKVN classically presents as allograft dysfunct...
متن کاملIncidence and outcomes of BK virus allograft nephropathy among ABO- and HLA-incompatible kidney transplant recipients.
BACKGROUND AND OBJECTIVES ABO-incompatible kidney transplant recipients may have a higher incidence of BK virus allograft nephropathy (BKVAN) compared with ABO-compatible recipients. It is unclear whether HLA-incompatible recipients share this risk or whether this phenomenon is unique to ABO-incompatible recipients. DESIGN, SETTING, PARTICIPATION, MEASUREMENTS: This study analyzed adult inc...
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ژورنال
عنوان ژورنال: Renal Failure
سال: 2019
ISSN: 0886-022X,1525-6049
DOI: 10.1080/0886022x.2019.1617168